Studies of molecular interactions using physical techniques. by Padungkiart Polanum

Cover of: Studies of molecular interactions using physical techniques. | Padungkiart Polanum

Published by University of Aston in Birmingham, Department of Chemistry in Birmingham .

Written in English

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Open LibraryOL20308283M

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Three different physical methods were employed. Nuclear magnetic resonance (n.m.r.) spectroscopy was used to determine the nature and strength of the interactions and the geometry of the transient complexes formed.

Cryoscopic studies were used to provide information on. He is supervising a research group working on the theoretical study of atomic and molecular interactions, and is author or co-author of over scientific papers mostly published on international journals, and of one book on Molecular Quantum Mechanics.

This book describes the methods of experimental spectroscopy and their use in the study of physical phenomena. The applications of optical spectroscopy may be grouped under three broad headings: chemical analysis, elucidation of atomic and molecular structure, and investigations of the interactionsBrand: Springer Netherlands.

The analysis of molecular interactions can result in the development of a biosensor: a device that is composed of a biological element and a physico-chemical transduction part that converts signal reception by the biological entity into a physical quantifiable response.

New processing methods govern the progress in physical-chemical technology. The potential of supercritical fluid methods is presented in a comprehensive way in this book.

On the basis of a careful discussion of physical and chemical principles, the application of this method 3/5(1). Advances in the tools and techniques of macromolecular structure analysis and representation have transformed molecular biology from a descriptive study of the basic genetic phenomena to a more mechanistic investigation based on considerable structural.

Several DSC studies have given a better understanding of the molecular mechanisms of interaction of many non-steroidal anti-inflammatory agents (NSAIDs), such as indomethacin, ibuprofen, naproxen, nimesulide, ketoprofen and oxicam drugs with cell membranes or with simplified phospholipid-based biomembrane models.

'Methods of Molecular Analysis in the Life Sciences is a much needed overview of the key analytical techniques currently utilized for biomolecule characterization in the life sciences including mass spectrometry, x-ray crystallography and a host of other by: 2.

Conclusion and Outlook. MST is an equilibrium method in bulk solution for the analysis of a broad range of molecular interactions. It measures the mobility of a fluorescently labeled molecule in a temperature field (Thermophoresis) and the sensitivity of fluorescence yield on temperature (MST T-Jump).Cited by: Single-Molecule Techniques: A Laboratory Manual fills this requirement—it is the first to take researchers who know nothing about single–molecule analyses to the point where they can successfully design and execute appropriate experiments.

Geared toward research scientists in structural and molecular biology, biochemistry, and biophysics.

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